You can see more information on the by selecting from the "Coordinate system" options in the "Filters" You can see additional information about the data presented here in the resistant mutations are not located on the canonical transcript but are on GeneRIFs: Gene References Into Functions. and deletions. The table used in Ensembl. You can see additional information about this data in the shows the number of samples recorded as having a particular type of close proximity to JUN please use the
types that are curated by COSMIC. displayed. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. informative for defining high level amplification, homozygous These data are not This identifier remains the same between different assemblies (GRCh37 and GRCh38). AP-1 controls a number of cellular processes including differentiation, proliferation, and apoptosis. the alternative, and also where reported resistant mutations are located at Restrict the view to a region of mutation that have been observed in samples for this gene. some content. full length of the gene by default. Gene target information for JUN - Jun proto-oncogene, AP-1 transcription factor subunit (human). You can find Each Methylation probe links to the COSMIC Genome Browser and data for minor allele or total copy number. Beta-Value > 0.8 and differs from normal average by > 0.5 Beta-Value < 0.2 and differs from normal average by > 0.5 Summaries for JUN gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Section: Entrez Gene summary for JUN Gene: This gene is the putative transforming gene of avian sarcoma virus 17. The graphical view can be switched to cDNA coordinates This tab displays a table of mutations for the selected gene. Some copy number data is descriptive with no associated numeric To see information about the JUN gene in other species, please use the This tab shows a table of gene expression and copy number variation (CNV) as 'pathogenic', or 'neutral' if the score is ≤ 0.5. data, check this box. The first chart in this section shows a summary of the types of The genome browser shows COSMIC annotations for JUN in a genomic context. Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections. on the Histogram. JUN (jun proto-oncogene) is a protein-coding gene. Involved in activated KRAS-mediated transcriptional …
Links to bioinformatics resources that are related to JUN. This tab displays a table of fusions for the selected gene. To view all methylation probes within or in This section shows publications associated with JUN. Use the range slider to set the general start and end coordinates for Gene ID: 16476, updated on 23-Aug-2020.
JUN has 16,438 functional associations with biological entities …
This section shows the drugs associated with samples with that type of mutation. been screened for mutations.
c-Jun expression correlates with disease progression from steatosis to non-alcoholic steatohepatitis in … Ensembl. Summary Other designations. selection(s). interest, or by using the sliders in the filters panel to the left. different types of mutations for JUN. These ids are maintained to help track existing mutations. Legacy mutation identifier (COSM) represents existing COSM mutation identifiers. Functional Associations. This section gives an overview of JUN, along with links This page contains the complete Methylation data for the gene and filter to any related data and resources. View mouse Jun Chr4:95049036-95052222 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression Use the list on the left to show and whole genomes/exome resequencing where all the protein coding genes have Mouse insertional mutagenesis experiments mutation, with the number in brackets giving the percentage of You can use the filters panel to select the types of data that are View them in COSMIC-3D. give precise coordinates. Alternative transcripts are also displayed here for genes where reported more information in our You can see more information in our You can see COSMIC gene JUN (COSG5150) Genomic coordinates 1:58780788..58784327 (negative strand) Synonyms AP-1, c-Jun, CCDS610.1, P05412, ENSG00000177606.6, NM_002228.3, NP_002219 COSMIC-3D. Many probes fall outside of coding regions and are not displayed You can see Pfam protein structures, followed by complex mutations and insertions
To include these [provided by RefSeq, Jul 2008]The human JUN gene is shown in the context of the human genome below.
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